“The combination of Bayes and Markov Chain Monte Carlo has been called "arguably the most powerful mechanism ever created for processing data and knowledge."
Almost instantaneously MCMC and Gibbs sampling changed statisticians' entire method of attacking problems. In the words of Thomas Kuhn, it was a paradigm shift. MCMC solved real problems, used computer algorithms instead of theorems, and led statisticians and scientists into a worked where "exact" meant "simulated" and repetitive computer operations replaced mathematical equations. It was a quantum leap in statistics.”