I haven't read a whole volume by Lupoff yet, but some of his stories were included in several Cthulhu Mythos anthologies. These stories had an sci-fi based, outre futuristic and proto-cyberpunky take on the motif. I would recommend The Discovery of the Ghooric Zone (About a bunch of transhuman cyborgs on a journey to Yuggoth) as an good example:
http://www.infinityplus.co.uk/stories...
He has also written a (historic?) novel about Lovecraft:
Lovecraft's Book