What's the Name of That Book??? discussion

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Joy in the Morning
SOLVED: Adult Fiction
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SOLVED. He always said "Crysake Annie!" when he got frustrated with his wife... [s]
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There was a lady, her name was Annie. She has a husband. They got married very young,. They had a baby girl. They lived on college campus where he worked to pay off his tuition. She ended up with cancer in her leg...
I have never forgotten the book but don't remember how it ended...
ANY help out there? You are my last hope!