Madame's Munchkins discussion

This topic is about
One Flew Over the Cuckoo’s Nest
The Title
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I dont see Chief breaking out of the window as him "escaping from the others". I see it as him being the first to fully embrace the advice of McMurphy. McMurphy would have wanted the able inmates to break the rules because I feel like he though it kept them sane and out of the clutches of Ratchet
Apple seed and apple thorn;
Wire, briar, limber lock,
Three geese in a flock.
One flew east,
And one flew west,
And one flew over the cuckoo's nest."
This is a nursery rhyme by Oliver Goldsmith and the source of inspiration for the tittle of Kesey's novel. Why do you think he chose to name the book using a line from this rhyme. Do you think it is of any significance?